Table 1.

Demographic characteristics of the IMABio3 cohort

Group	# of patients	Age	Gender	MMSE	CDR-SOB	PiB-GCI
CTRL	9	51–81	4F/5 M	29.3 ± 0.86	0	1.43 ± 0.30
AD-MCI	11	52–79	5F/6 M	24.3 ± 2.97	2.50 ± 1.07	2.75 ± 0.57
AD-D	9	51–81	8F/1 M	16.5 ± 3.36	7.21 ± 0.69	3.00 ± 0.54

The CDR-SOB (Clinical Dementia Rating, Scale Sum of Boxes) scale indicates the severity of dementia; no dementia (CDR = 0). The maximum score for the Mini-Mental State Examination (MMSE) is 30, with lower scores associated with greater cognitive deterioration

CTRL control; AD-MCI Alzheimer’s disease patients with mild-cognitive impairment; AD-D Alzheimer’s disease patients with dementia; F female; M male; CDR-SOB clinical dementia rating sum of the boxes; PiB-GCI ¹¹C‐labelled Pittsburgh compound B, Global cortical index