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. 2024 Jun 8;25:370. doi: 10.1186/s13063-024-08219-1
Grade Category Clinical description Objective criteria
0 Asymptomatic, no hemodynamically significant occlusive disease Normal results of treadmill/stress test
I 1 Mild claudication Treadmill exercise completed, postexercise AP is greater than 50 mmHg but more than 25 mmHg less than normal
2 Moderate claudication Symptoms between those of categories 1 and 3
3 Severe claudication Treadmill exercise cannot be completed, postexercise AP is less than 50 mmHg
II 4 Ischemic rest pain Resting AP of 40 mmHg or less, flat or barely pulsatile ankle or metatarsal plethysmographic tracing, toe pressure less than 30 mmHg
III 5 Minor tissue loss, nonhealing ulcer, focal gangrene with diffuse pedal ischemia Resting AP of 60 mmHg or less, ankle or metatarsal plethysmographic tracing flat or barely pulsatile, toe pressure less than 40 mmHg
6 Major tissue loss, extending above transmetatarsal level, functional foot no longer salvageable Same as for category 5

AP ankle pressure.