TABLE 2.
Comparison of productivities of shake flask and laboratory and pilot scale bioreactor cultivations using Ralstonia eutropha strains to produce P(HB‐co‐HHx) with tailored HHx contents.
| Strain | Carbon source | HHx range (mol% HHx) | Productivity (gPHA L−1 h−1) | Scale | Reference |
|---|---|---|---|---|---|
| Re2058/pCB113 | Fructose and canola oil | 7–15 |
0.32–1.49 0.45–1.04 |
Laboratory scale Pilot scale |
This study |
| Re2058/pCB113 | Fructose and canola oil | 2–17 | 0.07–0.16 | Laboratory scale | Santolin et al. (2023) |
| Re2058/pCB113 | Palm olein and fructose | 5–28 | 0.02–0.12 | Laboratory scale | Murugan et al. (2017) |
| Re2058/pCB113 | Crude palm kernel oil and oil palm tree trunk sap | 14–27 | 0.03–0.09 | Shake flask | Murugan et al. (2016) |
| Re2058/pCB113 | Date seed oil and date molasses | 2–39 | <0.01–0.07 | Shake flask | Purama et al. (2018) |
| β‐ketothiolase deletion strains | Palm kernel oil | 14–32 | 2.64–2.88 | Laboratory scale | Arikawa and Sato (2022) |
| phaJ expression‐controlled rec. strains | Palm kernel oil | 6–15 | 2.49–2.57 | Laboratory scale | Arikawa and Matsumoto (2016) |
| ASBK | Butyrate and palm kernel oil | 7–13 | 1.74–2.12 | Laboratory scale | Sato et al. (2015) |
| phaC Ac in vitro evolution of rec. strains | Soya bean oil | 3–10 | 0.05–0.07 | Shake flask | Mifune et al. (2010) |
| phaC Ac rec. strains | Octanoate | 4–13 | 0.05–0.06 | Shake flask | Mifune et al. (2008) |
| ΔphaB1 Ccr rec. strains | Fructose | 0–22 | <0.01–0.01 | Shake flask | Insomphun et al. (2015) |