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. 2024 May 9;16(5):e59962. doi: 10.7759/cureus.59962

Table 7. Specificities of patient’s lung biopsy diagnostic down-regulated markers.

BC: breast carcinoma; HGSOC: high-grade serous ovarian carcinoma; LUAD: lung adenocarcinoma; LUSC: lung squamous cell carcinoma; PM: peritoneal mesothelioma

Note: The pertinent up-regulated marker, calretinin, should not be used as a standalone finding due to high sensitivity for malignant peritoneal mesothelioma and ~10% specificity for adenocarcinoma

Present markers  LUAD  LUSC  BC  HGSOC  PM 
Paired box gene 8 (PAX8) 6-18% 
Estrogen receptor (ER)  0-2% 
Progesterone receptor (PR)  0-7% 
Wilms tumor gene 1 (WT1)  0%  0-2%  0-3%  15-65% 
Podoplanin (D2-40)  0-3%  15-42%  0-3%  15-65%