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. 2024 Jun 8;7:706. doi: 10.1038/s42003-024-06338-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — (a) in the river dataset, (b) in the soil dataset. Values are displayed after transformation to log10 scale. The list of ARGs is presented based on similarity in abundance patterns and displayed from high abundance (red) to below the detection limit (blue). Color coding on the right displays the class of antibiotics they confer resistance to. Samples are ordered according to similarity in ARG profiles represented by the dendrogram on top based on default Euclidian clustering from the ComplexHeatmap R package⁷⁹ and color coded based on country of origin.