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. 2024 Jun 8;15:4901. doi: 10.1038/s41467-024-49215-y

Fig. 2. SPECO-based genome mining of ACyP BGCs.

Fig. 2

a A total of 1172 precursor peptides were identified by SSN analysis, which are categorized to 67 clusters. The sequence logo of each cluster was shown in Supplementary data 2. Previously characterized precursors are highlighted as black dots (microbisporicin and NAI-107 are synonyms and not distinct molecules). Two BGC families characterized in this study are boxed. b BGC architecture and core peptide sequence logo of the mat BGC family. Oxidoreductase and precursor were highlighted by arrow and triangle, respectively. The black connector denotes Avi(Me)Cys ring formation. c BGC architecture and core peptide sequence logo of the sis BGC family. Cys residues were highlighted by solid triangles.