Table 1.
Typical agents recommended for TGD adults undergoing hormone therapy
| Regimen | Typical Medication Classes | Prescribed Agents |
|---|---|---|
| Testosterone treatment | ||
| • Androgenic agent | • Testosterone (gel, compounded cream, or injection) | |
| Estrogen treatment a | ||
| • Estrogenic agent • Antiandrogenic agent |
• 17β-estradiol (tablet, patch, or injection) • Cyproterone acetate b, spironolactone, or gonadotropin agonist (e.g., leuprolide acetate) |
Table modified from Hembree et al., 2017 & Coleman et al., 2022. This table provides an overview of hormone therapies that may be recommended for TGD people. It not a comprehensive list of all agents that might be prescribed in clinical practice.
a
Clinical providers may add-on oral progestogens (e.g., micronized progesterone) or 5α-reductase inhibitors (e.g., finasteride) to support a person’s gender expression goals.
b
Not approved in the United States.