Table 1.

Mean total sodium concentrations of healthy volunteers’ fibroglandular tissue of the right and left breasts without and with B₁ corrections

		Non-B1-corrected (crude)			B1-correcteda
ROI method	Reader	Right (mmol/L)	Left (mmol/L)	p-value	Right (mmol/L)	Left (mmol/L)	p-value
Large ROI mean	Reader 1a	101.0 ± 37.4	92.0 ± 23.2	0.15	57.7 ± 19.7	53.6 ± 13.0	0.34
	Reader 2a	109.9 ± 39.5	100.9 ± 28.6	0.23	62.8 ± 20.1	58.1 ± 14.5	0.29
Small ROI mean	Reader 1a	137.5 ± 54.0	126.9 ± 35.6	0.25	77.5 ± 26.4	73.4 ± 17.8	0.52
	Reader 2a	137.8 ± 49.8	128.7 ± 30.5	0.41	78.5 ± 25.1	74.4 ± 16.1	0.56

The results are shown for the readers’ large and small regions of interest (ROIs); p-value denotes the statistical difference between the right- and left-sided measurements

^aPhantom’s signal intensity and B₁ measurement measured by Reader 1 was used to minimise the effect of differences caused by phantom ROI placement that contributes to B₁-corrected measurements