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Central hypothyroidism. (A) Case 3, (B) Case 4, (C) Case 5 and (D) Case 6 shows start of levothyroxine and changes in TSH and FT4. Case 4 was started on carbimazole (CBZ) at day 7 of life and was weaned off CBZ at day 45 of life when TFT revealed TSH 0.005 mU/L and FT4 16.2 pmol/L. Case 4 was started on levothyroxine at Day 66 of life.
