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. 2024 Jun 4;11(1):e002148. doi: 10.1136/bmjresp-2023-002148

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Biological functional and tissue and single cell-specific enrichment of candidate pleiotropic genes. (A) Top five pathways most significantly enriched for GO and KEGG gene sets. (B) Tissue-specific enrichment analysis using the PCGA (based on GTEx and PanglaoDB) identified top five significantly enriched tissues and single cell (p adjusted <0.05). BP, biological process; CC, cellular component; KEGG, Kyoto Encyclopaedia of Genes and Genomes; GO, Gene Ontology; GTEx, Genotype-Tissue Expression; KEGG, Kyoto Encyclopaedia of Genes and Genomes; MF, molecular function.