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Replication of recombinant FMDV variants in BHK-21 cells. Monolayers of BHK-21 cells were infected with chimeric viruses harboring the capsid of C-S8c1 (A), C-S8c1p100 and its RGG derivative (B), or C-S8c1p213 and its RGG derivative (C) at a multiplicity of infection of 5 PFU per cell. Procedures for the infection in liquid culture and titration of infectivity are described in Materials and Methods. Each value represents the mean of triplicate assays.
