TABLE 2.
Clinicopathological factors | Univariate analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Sex (male/female) | 2.845 | 0.939 to 8.625 | 0.07 | 3.697 | 0.771 to 17.733 | 0.10 |
Age (≥65/<65 y) | 2.951 | 0.770 to 11.300 | 0.11 | - | - | - |
Tumor size (>1.5/≤1.5 cm) | 5.052 | 1.688 to 15.120 | 0.004 | 5.654 | 1.228 to 26.043 | 0.03 |
Distance from the anus (>7/≤7 cm) | 0.833 | 0.243 to 2.864 | 0.77 | - | - | - |
T stage (T3+T4/T1+T2) | 5.753 | 1.576 to 21.000 | 0.008 | 1.202 | 0.271 to 5.337 | 0.82 |
Distant metastasis (positive/negative) | 36.410 | 4.364 to 303.800 | <0.001 | 4.191 | 1.233 to 14.244 | 0.02 |
Microvascular invasion (positive/negative) | 5.344 | 1.028 to 27.780 | 0.046 | 0.695 | 0.165 to 2.927 | 0.93 |
Perineural invasion (positive/negative) | 3.250 | 0.403 to 26.200 | 0.268 | - | - | - |
Statistically significant (p <0.05) values are in bold.