FIG. 4.

The structural changes that accompany HSV-1 capsid maturation are characterized by comparing the hexons (a and b) and pentons (c and d) of the m100 procapsid (a and c) and the mature capsid (A capsid; b and d). The outer surfaces are shown in each case. Panels a and b are centered on the E hexon which resides at each twofold axis and includes portions of the surrounding P and C hexons (for nomenclature, see the legend to Fig. 3). In the left halves of panels a and c, the less ordered density associated with the immunoprecipitating 6F10 antibodies is present, whereas it has been computationally removed in the right halves. The resolution is 18 Å. Bar = 100 Å.