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Median serum levels of daidzein in Japanese men given oral isoflavone (60 mg/day) or placebo for 12 months (n = 158). Daidzein was significantly increased in the isoflavone groups, and its level was lower in individuals who could also degrade daidzein into equol (isoflavone/producer group) compared with those who could not (isoflavone/non‐producer group).
