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Serum prostate‐specific antigen (PSA) levels in Japanese men given oral isoflavone (60 mg/day) or placebo for 12 months (n = 158). The PSA value showed no significant change during the study. There were also no differences among the treatment groups. Non‐producers, individuals unable to degrade daidzein into equol; producers, individuals able to degrade daidzein into equol.
