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. 2011 Nov 8;103(1):17–25. doi: 10.1111/j.1349-7006.2011.02111.x

Figure 5.

Figure 5

 Adoptively‐transferred human CD8+ T cells infiltrate into tumor tissues. Tumor specimens were harvested from non‐obese, diabetic/SCID/γcnull mice 14 days after subcutaneous inoculation with 2.5 × 106 KE4 or QG56 tumor cells, and intravenous administration of 1 × 108 gene‐modified or unmodified cells or PBS (control). We stained formalin‐embedded tumor specimens with an antihuman CD8 monoclonal antibody, clone C8/144B. Average CD8+ TIL counts ± SD in KE4 or QG56 (A) and the representative images from KE4 tissue sections (B) are shown.