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. Author manuscript; available in PMC: 2024 Jun 10.
Published in final edited form as: Biomaterials. 2016 Dec 2;118:84–93. doi: 10.1016/j.biomaterials.2016.12.001

Figure 5.

Figure 5.

Effects of stabilizers on physicochemical properties and delivery of efficacy of siLuc PE4K-A13-0.33C6 (C6-siLuc) NPs and siLuc PE4K-A13-0.33C10 (C10-siLuc) NPs. a) Size (Dh) and surface charge (ζ) of polyester NPs, and b) in vitro siRNA delivery efficacy of NPs (mean ± s.d., n = 3). 5% or 10% (weight ratio of stabilizer to the polymer) stabilizers (PEG lipid, F-68, or F-127) were added into the polymer stock solution before mixing with siLuc. NPs were prepared using the same protocol in screening assays and 17.1 nM siLuc was used.