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. 2024 Jun 10;14:13352. doi: 10.1038/s41598-024-64189-z

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gross pathology and imaging of bovine liver frozen following injection of POL22 with and without DOX. (a) Cut liver showing injections of POL22 with iodine, without DOX (left) and with 2 mg/mL of DOX (right). The injection core (asterisk) and gel extending into liver tissue (yellow arrow) are shown. (b) Gross image of the tissue section (left) and corresponding cone beam CT image (right) for 4 mL (top, white arrow) and 14 mL (bottom, arrow head) injections of POL22 with iodine but without DOX.