Table 2.
Molecular docking: established inhibitors against VEGFR-1.
| PubChem ID | Name | MolDock score (KJ/mol) | Re-rank score (KJ/mol) | MW (g/mol) |
|---|---|---|---|---|
| [00] 25102847 | Cabozantinib | − 155.779 | − 112.901 | 501.506 |
| [01] 25102847 | Cabozantinib | − 141.584 | − 107.22 | 501.506 |
| [04] 208908 | Lapatinib | − 133.312 | − 103.862 | 581.058 |
| [01] 10297043 | AEE-788 | − 139.967 | − 102.39 | 440.583 |
| [01] 208908 | Lapatinib | − 136.122 | − 101.227 | 581.058 |
| [01] 11234052 | Brivanib | − 128.031 | − 100.245 | 370.378 |
| [00] 6450551 | Axitinib | − 122.085 | − 99.9181 | 386.47 |
| [02] 9933475 | Cediranib | − 130.775 | − 98.8826 | 450.505 |
| [04] 10297043 | AEE-788 | − 128.374 | − 98.5575 | 440.583 |
| [03] 25017411 | Anlotinib | − 126.322 | − 98.0086 | 407.437 |
| [00] 442126 | Decursin | − 122.708 | − 97.7696 | 328.359 |