Table 4.
Molecular docking: Established inhibitors against VEGFR-3.
| PubChem ID | Name | MolDock score (KJ/mol) | Re-rank score (KJ/mol) | MW (g/mol) |
|---|---|---|---|---|
| [02] 208908 | Lapatinib | − 158.144 | − 118.195 | 581.058 |
| [00] 9911830 | Tivozanib | − 144.231 | − 113.369 | 454.863 |
| [03] 208908 | Lapatinib | − 152.213 | − 109.955 | 581.058 |
| [01] 25102847 | Cabozantinib | − 133.435 | − 108.037 | 501.506 |
| [01] 17536 | Oxypeucedanin hydrate | − 134.001 | − 106.623 | 304.295 |
| [00] 6398883 | AAL-993 | − 129.671 | − 106.112 | 371.356 |
| [01] 10297043 | AEE-788 | − 124.179 | − 105.301 | 440.583 |
| [04] 208908 | Lapatinib | − 148.129 | − 104.772 | 581.058 |
| [04] 5329102 | Sunitinib | − 136.513 | − 103.711 | 398.474 |
| [02] 6398883 | AAL-993 | − 121.182 | − 101.047 | 371.356 |
| [02] 25017411 | Anlotinib | − 129.917 | − 100.759 | 407.437 |