TABLE 3.

Predictive efficiency of pharmacogenetic predictors for amoxicillin-induced severe cutaneous adverse reactions.

Predictor	Carrier, No. (%)		P	OR (95% CI)	Sensitivity (%)	Specificity (%)
	AMX-SCAR (4)	AMX-tolerant controls (100)
HLA-B*15:01	3 (75)	11 (11)	7.34 × 10−3	22.9 (1.64–1262.54)	75	89
T538	3 (75)	11 (11)	7.34 × 10−3	22.9 (1.68–1275.67)	75	89
C419	4 (100)	13 (13)	5.18 × 10−4	53.5 (2.67–1072.29)	100	87

Abbreviations: AMX, amoxicillin; SCAR, severe cutaneous adverse reaction; OR, odds ratio; CI, confidence interval.