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Funnel plots and subgroup analyses comparing the risks of MACE (A), myocardial reinfarction (B), and HF (C) with sacubitril–valsartan vs. ACEI/ARB in AMI patients after PPCI. ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker. MACE, major adverse cardiac event; HF, heart failure.
