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. 2024 May 28;12:1414005. doi: 10.3389/fbioe.2024.1414005

TABLE 2.

Changes in body weight of mice before and after intraperitoneal injection ( x¯ ±s, g).

Groups n Weight change at different time points
Day 1 Day 2 Day 3
Normal saline 5 0.56 ± 0.52 0.79 ± 0.46* 0.62 ± 0.50*
PMMA 5 0.61 ± 0.17 0.78 ± 0.17* 0.70 ± 0.09*
5%N-Cl 5 0.60 ± 0.21 0.83 ± 0.18* 0.90 ± 0.29*
10%N-Cl 5 0.23 ± 0.36 0.49 ± 0.37* 0.70 ± 0.42*
15%N-Cl 5 0.56 ± 0.56 0.74 ± 0.66* 0.56 ± 0.80
20%N-Cl 5 0.59 ± 0.54 0.74 ± 0.65* 0.74 ± 0.74*
25%N-Cl 5 0.31 ± 0.52 0.44 ± 0.58* 0.69 ± 0.64*
Fintergroup/time/interaction P intergroup/time/interaction 0.278/21.623/2.374 0.943/<0.001/0.021

Note: Fintergroup represents the overall comparison of mouse body weight changes at the same time points between the PMMA, bone cement group and the groups with 5%, 10%, 15%, 20%, and 25% N-halamine compound monomer added bone cement, respectively, compared with the saline group (blank control group), and the comparison with the saline group at the same time points showed p > 0.05.

Ftime represents the overall comparison of mouse body weight changes at different time points within each group compared with the body weight change at day 1, and compared with the body weight change at day 1, * indicates p < 0.05.