Figure 4.

Mammalian confirmed-canonical alignments are similar to bacterial alignments. (A) One hundred samples of percent identity across the 5244 pairs of sequences for which canonical changes were proposed (circles) and 100 samples from the distribution of identities shown in Figure 1A for E. coli versus S. typhimurium and S. cerevisiae versus S. arboricola. (B) Distribution of gap sizes for the 100 samples shown in (A), plus all alignments with a maximum gap length >50, and the longest 25 gaps. (C) The percentage of alignments with gaps ≥5 residues versus alignment percent identity for all the pairwise alignments shown in (A). The distributions of ecoli:salty and yeast:sacar alignments in panels A–C replot the data shown in Figure 1.