Table 3.
Occupational exposure to carcinogenic agents among subjects with sinonasal cancer (SNC)a, by gender and tumour morphology, Lombardy Region SNC Registry, Italy, 2008–20
| SCC | Adenocarcinoma | Otherb | P valuec | |
|---|---|---|---|---|
| Occupational exposure | n (%) | n (%) | n (%) | |
| Men | 220 (100) | 201 (100) | 60 (100) | |
| Never exposed | 176 (80) | 50 (25) | 40 (67) | |
| Ever exposed (any agent) | 44 (20) | 151 (75) | 20 (33) | <0.001 |
| Ever exposed to: | ||||
| Wood dust | 31 (14) | 103 (51) | 15 (25) | <0.001 |
| Leather dust | 8 (4) | 50 (25) | 6 (10) | <0.001 |
| Nickel compounds | 3 (1) | 3 (1) | 3 (5) | 0.16 |
| Chromium compounds | 7 (3) | 7 (3) | 2 (3) | 0.98 |
| Formaldehyde | 1 (0) | 2 (1) | 0 (0) | 0.63 |
| Women | 117 (100) | 69 (100) | 32 (100) | |
| Never exposed | 102 (87) | 53 (77) | 27 (84) | |
| Ever exposed (any agent) | 15 (13) | 16 (23) | 5 (16) | 0.18 |
| Ever exposed to: | ||||
| Wood dust | 6 (5) | 6 (9) | 1 (3) | 0.47 |
| Leather dust | 6 (5) | 11 (16) | 3 (9) | 0.05 |
| Nickel compounds | 1 (1) | 0 (0) | 2 (6) | 0.03 |
| Chromium compounds | 2 (2) | 0 (0) | 1 (3) | 0.41 |
| Formaldehyde | 1 (1) | 0 (0) | 0 (0) | 0.65 |
A subject may have been exposed to more than one agent in his/her occupational history. SCC, squamous cell carcinoma and variants.
aIncluded: 699 subjects (481 men, 218 women) with interview and morphology.
bIncluded: neuroendocrine carcinoma, other morphology, malignant tumour.
cFrom chi-squared test.