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Schematic illustration of PD‐L1‐targeted PTEN/Pep LNPs for immunotherapy of TNBC. a) Scheme for the assembly of Pep LNPs with mRNA. b) Targeted delivery of PTEN/Pep LNPs to PD‐L1‐high tumors induces PTEN‐mediated autophagy and ICD, promotes DC maturation, and stimulates CD8+ T cell infiltration, enhancing antitumor immunity.
