Table 2.
Demographics and Initial Treatment
| Patient | Age at Dx (months) | Sex | Stage | Extent of initial resection | Histology | Group | Upfront radiation | Upfront chemotherapy |
|---|---|---|---|---|---|---|---|---|
| 1 | 75 | F | M0 | GTR | Classic | 4 | CSI 2340cGy + boost 3060cGy | Maintenance: CCNU, VCR, CP, CPM (9 cycles) |
| 2 | 53 | F | M0 | GTR | Classic | 3 | n/a | Induction: CP, CPM, ETOP, VCR, MTX (6 cycles) Consolidation: HDC carboplatin, thiotepa, etoposide with AuSCR (1 cycle) |
| 3 | 65 | M | M3 | STR | Anaplastic | 4 | Spinal 2310cGy then cranial 1800cGy + boost 5400cGy | Induction: CP, CPM, ETOP, VCR, MTX (3 cycles), metronomic cyclophosphamide and etoposide, maintenance with cis-retinoic acid and vorinostat |
| 4 | 107 | M | M3 | GTR | Classic | 4 | CSI 3600cGy + boost 1980cGy | Maintenance: CP, CPM, VCR (6 cycles) |
| 5 | 210 | M | unk | unk | unk | unk | CSI 4140cGy | n/a |
| 6 | 119 | M | M0 | STR | Classic | 4 | CSI 2340cGy + boost 3060cGy | Maintenance: CCNU, VCR, CP, CPM (9 cycles) |
| 7 | 31 | M | M0 | GTR | Classic | 3/4 | n/a | Induction: CP, CPM, ETOP, VCR, MTX (6 cycles) Consolidation: HDC carboplatin, thiotepa, etoposide with AuSCR (1 cycle) |
| 8 | 69 | F | M3 | GTR | Classic | 3/4 | n/a | Induction: CP, VCR, ETOP, CPM, MTX (3 cycles) |
| 9 | 36 | M | M4 | GTR | Anaplastic | Unk | n/a | Induction: CP, VCR, ETOP, CPM, MTX (5 cycles) |
M, male; F, female; GTR, gross total resection; STR, subtotal resection; unk, unknown; VCR, vincristine; CP, cisplatin; CPM, cyclophosphamide; ETOP, etoposide; MTX, methotrexate.