Fig 2. Prenatal bisphenol exposure was associated with reduced eye-opening prevalence at PND 15 after accounting for postnatal licking/grooming from PND 1–5, particularly in male pups.

(A) No main effects of prenatal treatment were found for eye-opening prevalence at PND 15. Marginal interactions between prenatal treatment and postnatal licking/grooming were found for (B) total pups within a litter and (C) male pups only, but not (D) female pups only. After accounting for postnatal licking/grooming, all prenatal bisphenol exposure groups showed reduced eye-opening prevalence compared to the Corn Oil group for total pups within a litter and male pups only. Bar plots are displayed with mean +/- SEM with individual datapoints. Scatterplots are displayed with linear regression lines for each prenatal treatment group. * p < 0.05 main effect of prenatal treatment; ✤ p < 0.10 interaction between prenatal treatment and postnatal maternal care.