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. 2024 Jun 11;19(6):e0305256. doi: 10.1371/journal.pone.0305256

Fig 3. Prenatal bisphenol exposure was associated with reduced attentional set shifting performance after accounting for postnatal nest attendance from PND 1–5 for male and female offspring.

Fig 3

No main effects of prenatal treatment were found for (A) trials to reach criterion or (B) percent correct trials in the attentional set shifting response task. A marginal interaction between prenatal treatment and postnatal nest attendance was found for (C) percent correct trials for male offspring. A significant interaction between prenatal treatment and postnatal nest attendance was found for (D) trials to reach criterion for female offspring. After accounting for postnatal nest attendance, the 50 μg/kg BPA (male and female offspring) and 150 μg/kg Mixed BP (female offspring only) exposure groups showed reduced attentional set shifting performance compared to the Corn Oil group. Bar plots are displayed with mean +/- SEM with individual datapoints. Scatterplots are displayed with linear regression lines for each prenatal treatment group. * p < 0.05 main effect of prenatal treatment; ★ p < 0.05 interaction between prenatal treatment and postnatal maternal care; ✤ p < 0.10 interaction between prenatal treatment and postnatal maternal care.