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. 2024 Jun 11;19(6):e0305256. doi: 10.1371/journal.pone.0305256

Table 1. Summary of conditional post-hoc tests between the corn oil group and prenatal bisphenol treatment groups at the 16th, 50th, and 84th values of postnatal maternal care.

Outcome Variable Levels of Postnatal Maternal Care Prenatal Bisphenol Treatment Group Effect relative to Corn Oil +/- SEM t-value p-value*
Percent Eyes Open at PND 15 (Total Pups) Low Licking/Grooming (16th percentile) 50 μg/kg BPA -40.2951 +/- 21.9672 -1.8343 0.0747
50 μg/kg Mixed BP -50.3822 +/- 18.3301 -2.7486 0.0092
150 μg/kg Mixed BP -43.5898 +/- 17.8518 -2.4418 0.0195
Mid Licking/Grooming (50th percentile) 50 μg/kg BPA -10.8450 +/- 13.3596 -0.8118 0.4221
50 μg/kg Mixed BP -22.9496 +/- 12.5157 -1.8337 0.0748
150 μg/kg Mixed BP -11.6094 +/- 12.3743 -0.9382 0.3542
High Licking/Grooming (84th percentile) 50 μg/kg BPA 19.0713 +/- 17.0289 1.1199 0.2700
50 μg/kg Mixed BP 4.9173 +/- 17.3990 0.2826 0.7790
150 μg/kg Mixed BP 20.8772 +/- 17.5671 1.8840 0.2422
Percent Eyes Open at PND 15 (Males) Low Licking/Grooming (16th percentile) 50 μg/kg BPA -37.9521 +/- 22.3507 -1.6980 0.0979
50 μg/kg Mixed BP -63.9907 +/- 18.6500 -3.4311 0.0015
150 μg/kg Mixed BP -46.6656 +/- 18.1634 -2.5692 0.0144
Mid Licking/Grooming (50th percentile) 50 μg/kg BPA -10.9718 +/- 13.5928 -0.8072 0.4247
50 μg/kg Mixed BP -29.1892 +/- 12.7342 -2.2922 0.0277
150 μg/kg Mixed BP -16.5370 +/- 12.5903 -1.3135 0.1971
High Licking/Grooming (84th percentile) 50 μg/kg BPA 16.4357 +/- 17.3262 0.9486 0.3490
50 μg/kg Mixed BP 6.1633 +/- 17.7028 0.3482 0.7297
150 μg/kg Mixed BP 14.0685 +/- 17.8738 0.7871 0.4362
Percent Correct Trials in Attentional Set Shifting Task (Males) Low Nest Attendance (16th percentile) 50 μg/kg BPA -8.9412 +/- 4.9007 -1.8245 0.0766
50 μg/kg Mixed BP 3.0964 +/- 4.1020 0.7549 0.4554
150 μg/kg Mixed BP -0.1752 +/- 4.1374 -0.0424 0.9665
Mid Nest Attendance (50th percentile) 50 μg/kg BPA -3.4508 +/- 3.3205 -1.0392 0.3058
50 μg/kg Mixed BP 2.1978 +/- 2.9830 0.7368 0.4662
150 μg/kg Mixed BP 3.2182 +/- 2.9835 1.0787 0.2881
High Nest Attendance (84th percentile) 50 μg/kg BPA 4.4064 +/- 4.2295 1.0418 0.3046
50 μg/kg Mixed BP 0.9119 +/- 4.3840 0.2080 0.8364
150 μg/kg Mixed BP 8.0746 +/- 4.8408 1.6680 0.1042
Trials to Reach Criterion in Attentional Set Shifting Task (Females) Low Nest Attendance (16th percentile) 50 μg/kg BPA 32.1010 +/- 19.4303 1.6521 0.1083
50 μg/kg Mixed BP 8.7079 +/- 15.8739 0.5486 0.5871
150 μg/kg Mixed BP 41.9213 +/- 18.8537 2.2235 0.0334
Mid Nest Attendance (50th percentile) 50 μg/kg BPA 3.3268 +/- 13.3524 0.2492 0.8048
50 μg/kg Mixed BP -1.5408 +/- 11.7130 -0.1315 0.8962
150 μg/kg Mixed BP 7.3566 +/- 12.5510 0.5861 0.5619
High Nest Attendance (84th percentile) 50 μg/kg BPA -35.7009 +/- 17.3232 -2.0609 0.0475
50 μg/kg Mixed BP -15.4417 +/- 17.5670 -0.8790 0.3859
150 μg/kg Mixed BP -39.5251 +/- 22.8893 -1.7268 0.0938
Time Spent in Center of Open Field (Males) Low Nest Attendance (16th percentile) 50 μg/kg BPA 35.1964 +/- 19.6657 1.7897 0.0775
50 μg/kg Mixed BP 47.2734 +/- 19.1989 2.4623 0.0161
150 μg/kg Mixed BP 5.6697 +/- 21.4596 0.2642 0.7923
Mid Nest Attendance (50th percentile) 50 μg/kg BPA -18.4510 +/- 14.2794 -1.2921 0.2002
50 μg/kg Mixed BP -26.1659 +/- 14.0203 -1.8663 0.0659
150 μg/kg Mixed BP -28.6993 +/- 14.0125 -2.0481 0.044
High Nest Attendance (84th percentile) 50 μg/kg BPA -69.0385 +/- 21.0396 -3.2814 0.0016
50 μg/kg Mixed BP -95.4167 +/- 21.6009 -4.4173 < 0.0001
150 μg/kg Mixed BP -61.1081 +/- 23.6794 -2.5806 0.0118

*p < 0.10

p < 0.05