Table 1. Summary of conditional post-hoc tests between the corn oil group and prenatal bisphenol treatment groups at the 16th, 50th, and 84th values of postnatal maternal care.
Outcome Variable | Levels of Postnatal Maternal Care | Prenatal Bisphenol Treatment Group | Effect relative to Corn Oil +/- SEM | t-value | p-value* |
---|---|---|---|---|---|
Percent Eyes Open at PND 15 (Total Pups) | Low Licking/Grooming (16th percentile) | 50 μg/kg BPA | -40.2951 +/- 21.9672 | -1.8343 | 0.0747 |
50 μg/kg Mixed BP | -50.3822 +/- 18.3301 | -2.7486 | 0.0092 | ||
150 μg/kg Mixed BP | -43.5898 +/- 17.8518 | -2.4418 | 0.0195 | ||
Mid Licking/Grooming (50th percentile) | 50 μg/kg BPA | -10.8450 +/- 13.3596 | -0.8118 | 0.4221 | |
50 μg/kg Mixed BP | -22.9496 +/- 12.5157 | -1.8337 | 0.0748 | ||
150 μg/kg Mixed BP | -11.6094 +/- 12.3743 | -0.9382 | 0.3542 | ||
High Licking/Grooming (84th percentile) | 50 μg/kg BPA | 19.0713 +/- 17.0289 | 1.1199 | 0.2700 | |
50 μg/kg Mixed BP | 4.9173 +/- 17.3990 | 0.2826 | 0.7790 | ||
150 μg/kg Mixed BP | 20.8772 +/- 17.5671 | 1.8840 | 0.2422 | ||
Percent Eyes Open at PND 15 (Males) | Low Licking/Grooming (16th percentile) | 50 μg/kg BPA | -37.9521 +/- 22.3507 | -1.6980 | 0.0979 |
50 μg/kg Mixed BP | -63.9907 +/- 18.6500 | -3.4311 | 0.0015 | ||
150 μg/kg Mixed BP | -46.6656 +/- 18.1634 | -2.5692 | 0.0144 | ||
Mid Licking/Grooming (50th percentile) | 50 μg/kg BPA | -10.9718 +/- 13.5928 | -0.8072 | 0.4247 | |
50 μg/kg Mixed BP | -29.1892 +/- 12.7342 | -2.2922 | 0.0277 | ||
150 μg/kg Mixed BP | -16.5370 +/- 12.5903 | -1.3135 | 0.1971 | ||
High Licking/Grooming (84th percentile) | 50 μg/kg BPA | 16.4357 +/- 17.3262 | 0.9486 | 0.3490 | |
50 μg/kg Mixed BP | 6.1633 +/- 17.7028 | 0.3482 | 0.7297 | ||
150 μg/kg Mixed BP | 14.0685 +/- 17.8738 | 0.7871 | 0.4362 | ||
Percent Correct Trials in Attentional Set Shifting Task (Males) | Low Nest Attendance (16th percentile) | 50 μg/kg BPA | -8.9412 +/- 4.9007 | -1.8245 | 0.0766 |
50 μg/kg Mixed BP | 3.0964 +/- 4.1020 | 0.7549 | 0.4554 | ||
150 μg/kg Mixed BP | -0.1752 +/- 4.1374 | -0.0424 | 0.9665 | ||
Mid Nest Attendance (50th percentile) | 50 μg/kg BPA | -3.4508 +/- 3.3205 | -1.0392 | 0.3058 | |
50 μg/kg Mixed BP | 2.1978 +/- 2.9830 | 0.7368 | 0.4662 | ||
150 μg/kg Mixed BP | 3.2182 +/- 2.9835 | 1.0787 | 0.2881 | ||
High Nest Attendance (84th percentile) | 50 μg/kg BPA | 4.4064 +/- 4.2295 | 1.0418 | 0.3046 | |
50 μg/kg Mixed BP | 0.9119 +/- 4.3840 | 0.2080 | 0.8364 | ||
150 μg/kg Mixed BP | 8.0746 +/- 4.8408 | 1.6680 | 0.1042 | ||
Trials to Reach Criterion in Attentional Set Shifting Task (Females) | Low Nest Attendance (16th percentile) | 50 μg/kg BPA | 32.1010 +/- 19.4303 | 1.6521 | 0.1083 |
50 μg/kg Mixed BP | 8.7079 +/- 15.8739 | 0.5486 | 0.5871 | ||
150 μg/kg Mixed BP | 41.9213 +/- 18.8537 | 2.2235 | 0.0334 | ||
Mid Nest Attendance (50th percentile) | 50 μg/kg BPA | 3.3268 +/- 13.3524 | 0.2492 | 0.8048 | |
50 μg/kg Mixed BP | -1.5408 +/- 11.7130 | -0.1315 | 0.8962 | ||
150 μg/kg Mixed BP | 7.3566 +/- 12.5510 | 0.5861 | 0.5619 | ||
High Nest Attendance (84th percentile) | 50 μg/kg BPA | -35.7009 +/- 17.3232 | -2.0609 | 0.0475 | |
50 μg/kg Mixed BP | -15.4417 +/- 17.5670 | -0.8790 | 0.3859 | ||
150 μg/kg Mixed BP | -39.5251 +/- 22.8893 | -1.7268 | 0.0938 | ||
Time Spent in Center of Open Field (Males) | Low Nest Attendance (16th percentile) | 50 μg/kg BPA | 35.1964 +/- 19.6657 | 1.7897 | 0.0775 |
50 μg/kg Mixed BP | 47.2734 +/- 19.1989 | 2.4623 | 0.0161 | ||
150 μg/kg Mixed BP | 5.6697 +/- 21.4596 | 0.2642 | 0.7923 | ||
Mid Nest Attendance (50th percentile) | 50 μg/kg BPA | -18.4510 +/- 14.2794 | -1.2921 | 0.2002 | |
50 μg/kg Mixed BP | -26.1659 +/- 14.0203 | -1.8663 | 0.0659 | ||
150 μg/kg Mixed BP | -28.6993 +/- 14.0125 | -2.0481 | 0.044 | ||
High Nest Attendance (84th percentile) | 50 μg/kg BPA | -69.0385 +/- 21.0396 | -3.2814 | 0.0016 | |
50 μg/kg Mixed BP | -95.4167 +/- 21.6009 | -4.4173 | < 0.0001 | ||
150 μg/kg Mixed BP | -61.1081 +/- 23.6794 | -2.5806 | 0.0118 |
*p < 0.10
p < 0.05