Table 2. Precision diagnostic results of WGS routine diagnosis.
| Drug | WGS | BACTEC | CA (%) | Sensitivity | Specificity | Kappa Value (CI) | SE | |
|---|---|---|---|---|---|---|---|---|
| R | S | |||||||
| Rifampicin | R | 2 | 2 | 95.7 | 1.00 | 0.96 | 0.65 (0.20–1.00) | 0.23 |
| S | 0 | 43 | ||||||
| Isoniazid | R | 7 | 0 | 94.1 | 0.88 | 1.00 | 0.88 (0.66–1.00) | 0.12 |
| S | 1 | 9 | ||||||
| Pyrazinamide | R | 44 | 2 | 94.8 | 0.92 | 0.97 | 0.89 (0.81–0.98) | 0.04 |
| S | 4 | 66 | ||||||
| Moxifloxacin | R | 2 | 8 | 93.3 | 1.00 | 0.93 | 0.31 (-0.02–0.65) | 0.17 |
| S | 0 | 110 | ||||||
| Levofloxacin | R | 9 | 1 | 98.3 | 0.90 | 0.99 | 0.89 (0.74–1.00) | 0.08 |
| S | 1 | 109 | ||||||
| Amikacin | R | 2 | 0 | 100.0 | 1.00 | 1.00 | 1.00 (1.00–1.00) | 0.00 |
| S | 0 | 118 | ||||||
| Capreomycin | R | 8 | 0 | 99.2 | 0.89 | 1.00 | 0.94 (0.81–1.00) | 0.06 |
| S | 1 | 111 | ||||||
WGS: Whole genome sequencing, CA: Categorical agreement, SE: Standard error, CI: 95% Confidence interval, R: resistant, S: susceptible.