Fig. 1.

Gene expression analysis of cells differentiated using a cardiogenic protocol.

a) Principal component analysis of QuantSeq data from 4 WT to 4 Tbx1−/− biological replicates (independent differentiation experiments). Samples are clearly separated by genotype.

b) Volcano plot of gene expression values showing populations of differentially expressed genes. The individual values and gene names are listed in Suppl. Table 1

c-d) Top Gene Ontology/Cellular Component (GO:CC) terms identified for down regulated genes (c) and up regulated genes (d). Note the enrichment in ECM terms in the latter group. Full results with gene names are reported in Suppl. Table 2.