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. 2024 Aug 6;720:None. doi: 10.1016/j.bbrc.2024.150104

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© 2024 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 3 — Cardiac outflow tract phenotype in Minoxidil-treated Tbx1^neo2/lacZ fetuses (E16.5-E17.5). a-a'') H&E stained histological sections of a WT heart as reference. b-e) Examples of hearts from Minoxidil-treated Tbx1^neo2/lacZ fetuses. f) the incidence of septation defects (one OFT valve vs. two OFT valves) in Minoxidil-treated individuals is significantly lower than in vehicle-treated individuals (Chi-square test). IVS: Interventricular septum; LV: Left ventricle; RV: Right ventricle; VSD: Ventricular septal defect; PTA: Patent truncus arteriosus; IncTA: Incomplete septation of the arterial trunk; Ao: Aorta; P: Pulmonary trunk; DORV: Double outlet right ventricle. Scale bare: 100 μm.