Table 3.

Mixed regression model corrected for all interaction terms (contrast medium, reconstructions, vessel area; details in S1) and clinical characteristics. Significant p values are indicated in bold

	SNR			CNR
	Coef	95% Conf. Interval	p value	Coef	95% Conf. Interval	p value
Contrast medium
60 mL	Ref			Ref
50 mL	− 0.21	− 6.24–5.82	0.946	− 0.27	− 6.17 to 5.64	0.930
40 mL	− 1.10	− 7.23–5.04	0.726	0.00	− 6.04 to 6.04	0.999
30 mL	− 12.92	− 19.04 to − 6.81	< 0.001	− 13.86	− 19.87 to − 7.85	< 0.001
Reconstructions
Standard	Ref			Ref
VMI 40 keV	6.04	3.66–8.42	< 0.001	0.71	− 1.42 to 2.84	0.513
VMI 60 keV	− 9.80	− 12.19 to − 7.42	< 0.001	− 18.43	− 20.56 to − 16.30	< 0.001
Clinical characteristics
Age	0.23	0.03–0.44	0.027	0.16	− 0.07 to 0.38	0.174
Sex (female)	2.92	− 0.19 to 6.03	0.066	3.20	− 0.17 to 6.57	0.063
BMI	− 0.88	− 1.18 to − 0.57	< 0.001	− 0.83	− 1.17 to − 0.50	< 0.001
Agatston Score	0.00	− 0.00 to 0.00	0.423	0.00	− 0.00 to 0.00	0.704
Atrial fibrillation	2.37	− 0.80 to 5.55	0.143	3.40	− 0.05 to 6.84	0.053
Ejection fraction (normal (> 50%))	Ref
Moderately reduced (41–50%)	− 0.73	− 5.34 to 3.89	0.758	− 2.33	− 7.34 to 2.68	0.361
Reduced (31–40%)	− 2.89	− 8.93 to 3.15	0.348	− 4.17	− 10.72 to 2.39	0.213
Severely reduced (< 30%)	5.04	− 1.70 to 11.78	0.142	6.32	− 0.99 to 13.63	0.090

SNR, signal-to-noise ratio; CNR, contrast-to-noise ratio; BMI, body mass index