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Families identified with CHEK2 pathogenic mutations
(A–D) Family pedigrees carrying the CHEK2∗c.1100delC variant (E) Family pedigree carrying a CHEK2 c.1412C>T variant. Cancer types: Bn, brain; Br, breast; Col, colorectal; Cvx, cervix; Lng, lung; Oth, unknown source; Pro, prostate; Skn, skin; Stm, stomach; Utr, uterine.
