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. 2024 Jun 11;15:4927. doi: 10.1038/s41467-024-49289-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A summary figure showcasing observed expression in a number of genes and transcription factors of interest, with observed trends across all three different astronaut cohorts for samples obtained before flight (BF), in flight (IF) and after flight (AF). A number of genes relevant to the globin switch mechanism are shown on the left, while a number of selected genes of relevance to erythropoiesis are shown on the right.