Table 2.
Study | Total number | Intervention | Control | Aneurysm secured method | Target temperature (℃) | Induction time | Hypothermia time | Rewarming rate | Hypothermia method | Interval from onset to cooling | Shivering control system |
---|---|---|---|---|---|---|---|---|---|---|---|
Muroi et al. (2008) [13] | 15 | 7 | 8 | NA | 33 | NA | NA | NA | Endovascular cooling | NA | Yes |
Neuman et al. (2008) [14] | 37 | 25 | 12 | Coil | 34 | <3 hr | >72 hr | Passive warming | Surface cooling | Mixed (immediately or after admission 4–5 days) | No |
Anei et al. (2010) [15] | 35 | 19 | 16 | Clip or coil | 34 | NA | 48 hr | 1 °C/day | Surface cooling | <24 | No |
Karnatovskaia et al. (2014) [16] | 35 | 19 | 16 | Clip or coil | 32–34 | NA | >48 hr | <0.5 °C/hr | Surface cooling | NA | No |
Kuramatsu et al. (2015) [17] | 36 | 12 | 24 | Clip or coil | 35 | NA | 7±1 day | 0.5 °C/day | Endovascular cooling | <48 | Yes |
Choi et al. (2017) [18] | 22 | 11 | 11 | Clip or coil | 34.5 | <1 hr | 48 | 1 °C/day | Endovascular or surface cooling | <12 | Yes |
Shui et al. (2018) [19] | 62 | 30 | 32 | NA | 35 | 4–12 hr | 5–7 day | 1 °C/hr | Surface cooling | 2–8 hr | No |
Rhim et al. (2022) [20] | 54 | 18 | 36 | Coil | 34–35 | NA | 5 day | 0.5 °C/day | Surface cooling | <8 | Yes |
Won et al. (2022) [21] | 72 | 25 | 47 | Clip or coil | 34.5 | <1 hr | 48 hr | 1 °C/day | Endovascular or surface cooling | NA | Yes |
NA: not available.