Table 2.
Primary outcomes—comparison of numeric value indices prior and 3 months after POEM in achalasia study patients and in comparison with normal value indices of healthy controls
| Parameters | Prior to POEM (N=50) | 3 months post-POEM (N=50) | P value | 3 months post-POEM (N=50) | Healthy control (N=9) | P value |
| Eckardt score | <0.001* | |||||
| Mean (SD) | 6.53 (2.25) | 1.1 (1.45) | ||||
| Median (IQR) | 6 (3–12) | 0 (0–6) | ||||
| Tubular oesophagus (TE) (V×P), (cm³×mm Hg) | TE (0) | TE (3) | <0 .0001* | TE (3) | TE (N) | 0.010* |
| Mean (SD) | 3438.43 (3805) | 952.27 (1077.7) | 952.27 (1077.7) | 340.39 (396.7) | ||
| Median (IQR) | 2479.5 (164.77–17 879) | 682 (49–5133.5) | 682 (49–5133.5) | 209 (57.5–1337) | ||
| Lower oesophagus sphincter (LES) (V/P), (cm³/mmHg) | LES (0) | LES (3) | <0 .0001* | LES (3) | LES (N) | 0.077* |
| Mean (SD) | 0.1950 (0.3605) | 0.9955 (0.9966) | 0.9955 (0.9966) | 0.5269 (0.733) | ||
| Median (IQR) | 0.0548 (0.0001–2.26) | 0.6372 (0.03–4.51) | 0.6372 (0.03–4.51) | 0.3323 (0.03–2.36) |
*Mann-Whitney U test.
POEM, peroral endoscopic myotomy.