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. Author manuscript; available in PMC: 2024 Jun 12.
Published in final edited form as: Neuroimage. 2019 Nov 1;206:116317. doi: 10.1016/j.neuroimage.2019.116317

Table 2-.

Summary of ADNI dataset, the number of observations in each follow-up visit and the features extracted from each modality

Source* Number of observations Features
T1 T6 T12 T24 T36 T48
MRI 1465 1333 1191 987 617 451 Ventricular volume, Hippocampus volume, Whole Brain volume, Entorhinal Cortical thickness, Fusiform, Middle temporal gyrus, and intracranial volume (ICV)
PET 1127 1009 892 714 429 335 FDG, Pittsburgh Compound-B (PIB), AV45
Cognitive Test ** 1525 1357 1207 997 627 456 Rey Auditory Verbal Learning Test (RAVLT Immediate, RAVLT Learning, RAVLT Forgetting, RAVLT Perc Forgetting), Functional Activities Questionnaires (FAQ), Everyday Cognition (Ecog) scales: (EcogPtMem, EcogPtLang, EcogPtVisspat, EcogPtPlan, EcogPtOrgan, EcogPtDivatt, EcogPtTotal,EcogSPMem, EcogSPLang, EcogSPVisspat, EcogSPPlan, EcogSPOrgan, EcogSPDivatt, and EcogSPTotal)
CSF 1014 914 806 662 404 305 Amyloid Beta (ABETA), Phosphorylated Tau Protein (PTAU), and Total Tau Protein (TAU)
Risk factors 1737 Age, gender, years of education, and APOE4
*

In this table MRI refers to Magnetic Resonance Imaging, PET refers to Positron Emission Tomography, COG refers to Cognitive assessment tests and CSF refers to Cerebrospinal Fluid test.

**

The Mini-Mental State Examination (MMSE) and Clinical Dementia Rating Sum of Boxes (CDRSB) scores (since initially used for labelling subjects) and Alzheimer’s Disease Assessment Score (ADAS11, ADAS13) and the Montreal Cognitive Assessment (MoCA) (since highly correlated with MMSE) were excluded from the feature set in the training and testing phases of the proposed prediction model.