TABLE 3.
Clinical characteristics of the fertile group and recurrent implantation failure (RIF) group.
| Fertile (n = 23) | RIF (n = 23) | P‐value | |
|---|---|---|---|
| Female age, years | 34.2 (± 4.4) | 36.3 (± 3.9) | 0.095 |
| Female age groups | 0.074 | ||
| <35 years | 13 (56.5%) | 7 (30.4%) | |
| ≥35 years | 10 (43.5%) | 16 (69.6%) | |
| Female BMI, kg/m2 | 23.0 (20.7–25.9) | 23.7 (21.6–28.3) | 0.560 |
| Duration of infertility, months | 26.0 (20.0–38.0) | 29.0 (23.0–39.0) | 0.403 |
| Female smokers a | 1 (4.3%) | 1 (4.3%) | 1.000 |
| Type of infertility of the female b | 0.552 | ||
| Primary | 14 (60.9%) | 12 (52.2%) | |
| Secondary | 9 (39.1%) | 11 (47.8%) | |
| Cause of infertility c | 1.000 | ||
| Idiopathic | 9 (39.1%) | 8 (34.8%) | |
| Male factor | 13 (56.5%) | 12 (52.2%) | |
| Tubal factor | 1 (4.3%) | 2 (8.7%) | |
| Ovulatory disorder d | 0 | 1 (4.3%) | |
| No. of embryo transfers per participant | 2.4 (±0.5) | 5.7 (±2.5) | <0.001 |
| 1 | 15 (65.2%) | 0 | |
| 2 | 8 (34.8%) | 0 | |
| 3 | 0 | 5 (21.7%) | |
| 4 | 0 | 4 (17.4%) | |
| 5 | 0 | 3 (13.0%) | |
| 6 | 0 | 4 (17.4%) | |
| 7 | 0 | 1 (4.3%) | |
| 8 | 0 | 3 (13.0%) | |
| 9 | 0 | 2 (8.7%) | |
| 13 | 0 | 1 (4.3%) | |
| Total no. of embryos transferred, all participants | 60 | 153 | |
| No. of SET and DET | 0.379 | ||
| SET | 46 (86.8%) | 105 (81.4%) | |
| DET | 7 (13.2%) | 24 (18.6%) | |
| ET performed on day | <0.001 | ||
| 2 | 0 | 2 (1.3%) | |
| 3 | 51 (85.0%) | 78 (51.0%) | |
| 4 | 5 (8.3%) | 42 (27.5%) | |
| 5 | 4 (6.7%) | 29 (19.0%) | |
| 6 | 0 | 2 (1.3%) | |
| No. of fresh and frozen‐thawed ETs | <0.001 | ||
| Fresh | 52 (86.7%) | 74 (48.4%) | |
| Frozen‐thawed | 8 (13.3%) | 79 (51.6%) | |
| Embryonic stage | 0.005 | ||
| Cleavage stage embryo | 55 (91.7%) | 109 (71.2%) | |
| Morula | 1 (1.7%) | 14 (9.2%) | |
| Blastocyst | 4 (6.7%) | 30 (19.6%) | |
Note: Data are presented as mean (± SD), median (IQR) or number (%). The P‐value indicating the difference between mean number of embryo transfers per participant was determined by Independent Samples T‐test. All other P‐values were determined by Chi square test.
Abbreviations: BMI, body mass index; DET, double embryo transfer; ET, embryo transfer; SET, single embryo transfer.
Data was missing for one participant in the RIF group.
Primary: female has never conceived before. Secondary: female has conceived before.
No specific infertility diagnoses were excluded.
The woman in the RIF group with an ovulatory disorder had a WHO group III ovulatory disorder.