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. 2024 May 31;22(5):e3002639. doi: 10.1371/journal.pbio.3002639

Fig 7. Schematic of proteins in HCCU.

Fig 7

Section of infected RBC showing “initiation” phase of endocytosis (with strongly parasite-specific characteristics [3,15]) feeding into an endosomal transport pathway that depends on a functional complex of VPS45, Rbsn5L, and Rab5b (enlargement box) which indicates conserved elements playing a role in this phase of HCCU. FV, food vacuole; C, cytostome; E, endosome; PI3P, phosphatidylinositol-3-phosphate; RBC, red blood cell; PVM, parasitophorous vacuolar membrane; PPM (parasite plasma membrane); HCCU, host cell cytosol uptake; yellow arrow, direction of the pathway.