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. 2024 Mar 25;47(6):zsae081. doi: 10.1093/sleep/zsae081

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© The Author(s) 2024. Published by Oxford University Press on behalf of Sleep Research Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — (A) Significant associations between higher CSF IL-6 with longer sleep duration, longer time in bed, and higher PC3-Hypersomnia score. (B) Significant associations between higher CSF MCP-1 with longer sleep duration, later time of last morning awakening, and higher PC3-Hypersomnia score. (C) Significant associations between higher CSF PC-OLINK of inflammatory biomarkers with longer sleep duration and higher PC3-Hypersomnia score. All analyses are adjusted for age, sex and time interval between CSF collection and actigraphy. Betas are standardized. CSF, cerebrospinal fluid; PC3-Hypersomnia, third principal component of sleep characteristics representing a hypersomnia sleep pattern; PC-OLINK, single solution principal component of OLINK inflammatory biomarkers in the CSF.