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. 2024 May 8;630(8016):493–500. doi: 10.1038/s41586-024-07487-w

Extended Data Fig. 1. Disordered region prediction.

Extended Data Fig. 1

a, Example prediction for a disordered protein from AlphaFoldMultimer v2.3, AlphaFold 3, and AlphaFold 3 trained without the disordered protein PDB cross distillation set. Protein is DP02376 from the CAID 2 (Critical Assessment of protein Intrinsic Disorder prediction) set. Predictions coloured by pLDDT (orange: pLDDT <= 50, yellow: 50 < pLDDT <= 70, light blue: 70 < pLDDT <= 90, and dark blue: 90 <= pLDDT < 100). b, Predictions of disorder across residues in proteins in the CAID 2 set, which are also low homology to the AF3 training set. Prediction methods include RASA (relative accessible surface area) and pLDDT (N = 151 proteins; 46,093 residues).