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. 2024 May 22;630(8016):360–367. doi: 10.1038/s41586-024-07426-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — a, Representative immunofluorescence images at the adhesive implant-tissue interface on day 3 post-implantation to the abdominal wall. b, Quantification of iNOS + /neutrophil elastase+ and iNOS + /CD68+ cells per unit area on day 3 post-implantation for the adhesive implant-tissue interface. c, Representative immunofluorescence images at the non-adhesive implant-tissue interface on day 3 post-implantation to the abdominal wall. d, Quantification of iNOS + /neutrophil elastase+ and iNOS + /CD68+ cells per unit area on day 3 post-implantation for the non-adhesive implant-tissue interface. In immunofluorescence images, cell nuclei are stained with 4′,6-diamidino-2-phenylindole (DAPI, blue); green fluorescence corresponds to the expression of macrophage (CD68) and neutrophil (neutrophil elastase); red fluorescence corresponds to the expression of iNOS. *In images indicates the implant; white dotted lines in images indicate the implant-tissue interface. Values in b,d represent the mean and the standard deviation (n = 3 implants; independent biological replicates). Statistical significance and P values are determined by two-sided unpaired t-tests; ns, not significant; **P ≤ 0.01.