Fig. 2.

3-BrFlu induced integrity disruption and permeability increase in SVEC4-10 endothelial cells. The cells were incubated with 3-BrFlu at concentrations of 0, 3, 10, 50, and 100 μM for 24 h at 37 °C. A 3-BrFlu increased vascular endothelial integrity disruption through TEER measurements. B 3-BrFlu increased permeability through trans-endothelial albumin passage. All data are represented as the mean ± standard deviation of the mean (n = 3). Significant differences (P < 0.05) between the various treatment groups are indicated by the differential letter at the top of the columns