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. 2024 May 23;120:109789. doi: 10.1016/j.ijscr.2024.109789

Table 1.

Associations between the baseline clinicopathological features with OS in bladder metastatic malignant melanoma.

Characteristics N % OS (months)
p Value
(Mann-Whitney U test)
p Value
(Median test)
Mean SD Compare median (Median test) IQR
Gender Female 6 22.2 86.3 28.3 91.0 67.0–100.8 0.137 0.016
Male 21 77.8 66.8 84.9 21.0 12.0–124.0
Age group <40 1 3.7 6.0 N/A 6.0 N/A N/A
40–49 2 7.4 8.0 9.9 8.0 4.5–11.5
50–59 4 14.8 48.5 53.9 34.5 16.0–67.0
60–69 9 33.3 64.0 59.0 38.0 12.0–103.0
70–79 11 40.7 102.6 93.7 83.0 26.0–142.5
Primary site Skin 19 70.4 52.3 61.3 23.0 12.5–81.0 0.071 0.164
Mucosal 8 29.6 118.0 93.2 124.5 67.5–137.3
Bladder tumor No 1 14 51.9 93.7 91.5 71.5 16.5–147.8 0.175 0.123
≥ 2 9 33.3 37.6 45.4 16.5 12.5–44.5
Missing 4 14.8 N/A N/A N/A N/A



Synchronous metastasis
Synchronous metastasis No 7 25.9 117.8 101.9 103.5 56.8–130.0 0.15 0.321
Yes 20 74.1 58.9 65.2 24.5 11.0–96.3
Lymph node metastasis Absent 18 66.7 95.1 83.2 83.0 21.0–132.0 0.013 0.134
Present 9 33.3 29.9 39.9 12.0 6.0–28.0
Extranodal metastasis Absent 16 59.3 72.2 83.3 38.0 13.5–109.0 0.921 0.873
Present 11 40.7 73.0 71.8 60.0 14.5–114.0
Widespread Absent 23 85.2 75.1 79.08 54.0 14.3–118.8 0.973 0.644
Present 4 14.8 58.8 73.86 29.5 17.8–70.5



Metachronous metastasis
Metachronous metastasis No 13 48.1 53.1 65.83 24.5 12.5–70.8 0.275 0.175
Yes 14 51.9 89.2 84.34 85.5 15.0–130.0
Lymph node metastasis Absent 18 66.7 77.5 86.02 38.0 15.0–124.0 0.837 0.892
Present 9 33.3 63.2 60.21 48.0 12.0–94.0
Extranodal metastasis Absent 19 70.4 64.2 82.47 24.5 14.3–86.8 0.253 0.164
Present 8 29.6 91.4 64.2 109.0 37.5–137.3
Widespread Absent 24 88.9 64.5 63.83 38.0 13.0–113.5 0.44 0.946
Present 3 11.1 134.3 151.66 83.0 49.0–194.0
Gross hematuria No 10 37.0 78.4 70.54 60.5 19.8–117.8 0.558 1.0
Yes 14 51.9 59.2 54.2 38.0 15.8–99.8
Missing 3 11.1 N/A N/A N/A N/A