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. 2024 May 30;16:1394460. doi: 10.3389/fnagi.2024.1394460

TABLE 4.

Subjective cognitive decline (SCD) stratification: CSF biomarkers associated with meta-memory standardized residuals.

Predictors Non-SCD SCD
std. β (95% CI) p value std. β (95% CI) p value
Intercept 0.118 (−0.073, 0.310) 0.225 0.145 (−0.160, 0.450) 0.348
CSF p-tau181 −0.007 (−0.187, 0.174) 0.942 −0.006 (−0.279, 0.268) 0.968
CSF Aβ42/40 0.075 (−0.074, 0.225) 0.322 −0.328 (−0.570, −0.087) 0.008*
CSF (Aβ42/40)2 −0.166 (−0.318, −0.013) 0.034* −0.148 (−0.401, 0.105) 0.247
CSF p-tau181 x (CSF Aβ42/40)2 0.082 (−0.026, 0.191) 0.137 0.003 (−0.138, 0.144) 0.964

Sample was stratified by SCD-Q My-Cognition, non-SCD with n = 227, and SCD with n = 87. Results presented are standardized β coefficients, 95% Confidence Interval (CI), and p values derived from multivariable regression models using CSF Aβ42/40, and CSF p-tau181 as predictors of meta-memory standardized residuals adjusted for demographic characteristics (sex, age, and education). The p values in bold indicate a significant association (* < 0.050).