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. 2024 May 30;15:1399960. doi: 10.3389/fimmu.2024.1399960

Figure 3.

Figure 3

Screening of B cells from donor L5 leukopak with anti-idiotype antibodies identifies VH6-1 antibody with FG motif and different kappa chain from other members of the class. (A) Sorting of naïve and memory B cells from leukopak L5 with anti-idiotype antibodies. (B) Frequency of anti-idiotype positive naïve and memory B cells (C) Frequency of members with VH6-1 or FG motif in sequences isolated using anti-idiotype antibodies from leukopak L5. (D) VH-gene distribution of sequences isolated from leukopak L5 using anti-idiotype antibodies. (E) Venn diagram showing shared genetic elements among sequence members isolated using anti-idiotype antibodies. (F) Phylogenetic tree showing distance between L5A7 lineage members and MEDI8852. (G) Sequence features of L5A7 lineage members.