Table 1.

Afami-cel reactivity to MAGE-A4 peptides presented by different HLA-A2 subtypes, as determined in vitro using an IFN-γ cell-ELISA method following challenge of afami-cel with exogenous MAGE-A4 peptide in the context of MAGE-A4-negative tumor lines transduced with HLA-A2 subtypes

Transduced HLA-A∗02 allele	Average log(EC50) M
HLA-A∗02:01	−7.8
HLA-A∗02:02	−8.1
HLA-A∗02:03	−7.4
HLA-A∗02:05	−8.8
HLA-A∗02:06	−8.3
HLA-A∗02:07	−6.5

EC₅₀, half-maximal effective concentration; ELISA, enzyme-linked immunoassay; HLA, human leukocyte antigen; MAGE-A4, melanoma-associated antigen A4.