Table 2. Disease characteristics at the time of oligoprogression.
Variable | Values, n (%) |
---|---|
Type of immunotherapy (ICIs strategy) | |
Monotherapy | 4 (26.7) |
Combination | 7 (46.6) |
None | 4 (26.7) |
Lines of immunotherapy before oligoprogression | |
First line | 8 (53.3) |
Second line | 3 (26.7) |
None | 4 (26.7) |
Response to immunotherapy before oligoprogression | |
CR | 0 |
PR | 3 (20.0) |
SD | 12 (80.0) |
Number of oligoprogression | |
One | 12 (80.0) |
Two | 2 (13.3) |
Three | 1 (6.7) |
Organs of oligoprogression | |
Lung | 17 (85.0) |
Brain | 1 (5.0) |
Lymph node | 1 (5.0) |
Bone | 1 (5.0) |
Pattern of oligoprogression | |
New metastasis | 3 (20.0) |
Existing metastasis | 12 (80.0) |
Type of immunotherapy after oligoprogression | |
Monotherapy | 15 (100.0) |
Combination | 0 |
Change of ICIs strategy | |
Continue previous treatment or maintenance strategy | 6 (40.0) |
Adjusted maintenance strategy | 9 (60.0) |
ICIs, immune checkpoint inhibitors; SD, stable disease; PR, partial response; CR, complete response.